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Ho Kiong

Affiliation
Faculty of Medicine
Official title
Associate Professor
URL
Email
 
Research fields
Functional biochemistry
Parasitology (including sanitary zoology)
Molecular biology
Research keywords
RNA Processing, RNA ligation, Trypanosoma
Research projects
Mechanism of mRNA recapping pathway in trypanosome2016-04 -- 2020-03HO KIONG日本学術振興会/科研費/Scientific Research Basic B14,320,000Yen
Structural, Functional and Genetic Analysis of Archaea RNA Ligase2011-04 -- 2016-03Kiong HoNational Science Foundation/Div Of Molecular and Cellular Bioscience76,500,000Yen
Mechanism of mRNA cap formation in Trypanosoma brucei2006-07 -- 2011-06HO KIONGAmerican Heart Association/Scientist Development Grant26,000,000Yen
Mechanism of Archaeal RNA ligase2007-07 -- 2008-09HO KIONGUniversity at Buffalo/UB2020 Interdisciplinary Research Development Fund4,000,000Yen
Career history
2003-01 -- 2010-10State University of New York at Buffalo Department of Biological Sciences Assistant Professor
2000-01 -- 2003-10Sloan Kettering Instite for Cancer Research Program in Molecular Biology Senior Research Scientist
1997-04 -- 1999-12Sloan Kettering Institute for Cancer Research Program in Molecular Biology Post-doctoral Fellow
Academic background
1986-09 -- 1990-01Rutgers University, The State University of New Jersey College of Arts and Sciences B.A. BiochemistryGraduated
1990-09 -- 1997-03Cornell University, Weill Graduate School of Medical Sciences Ph.D. Molecular Biology Molecular BiologyGraduated
Academic societies
1997-01 -- (current)ASM (American Society of Microbiology)
2017-04 -- 2018-03THE JAPANESE SOCIETY OF PARASITOLOGY
2017-01 -- 2017-12RNA Society (International)
2017-04 -- 2018-03THE RNA SOCIETY OF JAPAN
-- (current)THE RNA SOCIETY OF JAPAN
-- (current)THE JAPANESE SOCIETY OF PARASITOLOGY
-- (current)RNA Society (International)
Articles
  • Teaching science and learning English: an introduction to the Molecular Biology Course in Vietnam
    Ho Kiong; Mayers Thomas; Ohneda Osamu
    Journal of Medical English Education/17(1)/pp.7-13, 2018-02
  • Cleavage of 3'-terminal adenosine by archaeal ATP-dependent RNA ligase
    Yoshinari Shigeo; Liu Yancheng; Gollnick Paul; Ho C Kiong
    Scientific reports/7(1), 2017-09
  • A Yeast-like mRNA Capping Apparatus in Plasmodium falciparum
    Ho CK; Shuman S
    Proc. Natl. Acad. Sci. USA/98(6)/pp.3050-3055, 2001-03
  • A Yeast-Based Genetic System for Functional Analysis of Viral mRNA Capping Enzymes
    Ho CK; Martins A; Shuman S
    JOURNAL OF VIROLOGY/74(12)/pp.5486-5494, 2000-06
  • RNA Triphosphatase Component of the mRNA Capping Apparatus of Paramecium bursaria Chlorella Virus
    Ho CK; Gong C; Shuman S
    JOURNAL OF VIROLOGY/75/pp.1744-1750, 2001-02
  • Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis
    Gu H; Yoshionari S; Ghosh R; Ignatochkina AV; Gollnick PD...
    Nucleic acids research/44(5)/pp.2337-2347, 2016-03
  • Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase
    Paul Smith; Ho Kiong; Yuko Takagi; Hakim Djaballah; Stewa...
    mBIO/7(1)/p.10.1128/mBio.00058-16 , 2016-02
  • The messenger RNA decapping and recapping pathway in Trypanosoma
    Ignatochkina AV; Takagi Y; Liu Y; Negate K; Ho Kiong
    Proceedings of the National Academy of Sciences USA/112(22)/pp.6967-6972, 2015-06
  • Teaching science and learning English: an introduction to the Molecular Biology Course in Vietnam
    Ho Kiong
    The Journal of Medical English Education/14(3)/pp.93-98, 2015-10
  • Archaea RNA Ligase is a Homodimeric Protein that Catalyzes Intramolecular Ligation of Single-Stranded RNA and DNA.
    Torchea C Takagi Y and Ho CK.
    Nucleic Acid Research/36/p.6218-6227, 2008-01
  • Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events.
    Dong H; Ray D; Ren S; Zhang B; Puig-Basagoiti F; Takagi Y...
    J. Virol./81/p.4412-4421, 2007-01
  • Trypanosoma brucei Encodes a Bifunctional Capping Enzyme Essential for Cap 4 Formation on the Spliced Leader RNA.
    Takagi Y Sindkar S Ekonomidis D Hall MP and Ho CK.
    J. Biol. Chem/282/p.15995-16005, 2007-01
  • Functional Characterization of a 48-kDa Trypanosoma brucei Cap 2 RNA Methyltransferase.
    Hall MP and Ho CK.
    Nucleic Acid Research/34/p.5594 - 5602, 2006-01
  • Characterization of a Trypanosoma brucei mRNA Cap (Guanine N-7) Methyltransferase.
    Hall MP and Ho CK.
    RNA/12/p.488 -497, 2006-01
  • Identification of the MicroRNAs of the Herpesvirus Family.
    Pfeffer S Sewer A Lagos-Quintana M Sheridan R Sander C Gr...
    Nature Method/2/p.269-276, 2005-01
  • Structure and Mechanism of RNA Ligase.
    Ho CK Wang LK Lima CD and Shuman S.
    Structure/12/p.327-339, 2004-01
  • Characterization of Bacteriophage KVP40 and T4 RNA Ligase 2.
    Yin S Ho CK Miller ES and Shuman S.
    Virology/319/p.141-151, 2004-01
  • Portability and Fidelity of RNA Repair Systems.
    Schwer B; Sawaya R; Ho CK; Shuman S.; +HO KIONG
    Proc. Natl. Acad. Sci. USA/101/p.2788-2793, 2004-01
  • Mutation Analysis of Bacteriophage T4 RNA Ligase 1: Differential Functional Group are Required for the Nucleotidyl Transfer and Phosphodiester Bond Formation Steps of the Ligation Reaction.
    Wang LK Ho CK Pei Y and Shuman S.
    J. Biol. Chem./278/p.17601-17608, 2003-01
  • RNA Substrate Specificity and Structure-Guided Mutational Analysis of T4 RNA Ligase 2.
    Nandakumar J Ho CK Lima CD and Shuman S.
    J. Biol. Chem./279/p.31337-31347, 2003-01
  • Bacteriophage T4 RNA Ligase 2 (gp 24.1) Exemplifies a Family of RNA Ligases Found in All Phylogenic Domains.
    Ho CK and Shuman S.
    Proc. Natl. Acad. Sci. USA/99/p.12709-12714, 2002-01
  • Tat Stimulates Cotranscriptional Capping of HIV-1 mRNA.
    Chiu YL; Ho CK; Saha N; Schwer B; Shuman S; and Rana TM.;...
    Molecular Cell/10/p.585-597, 2002-01
  • Importance of Homodimerization for the in vivo Function of Yeast RNA Triphosphatase.
    Lehman K Ho CK and Shuman S.
    J. Biol. Chem./276/p.14996-15002, 2001-01
  • Structure and Mechanism of the RNA Triphosphatase Component of Mammalian mRNA Capping Enzyme.
    Changela A; Ho CK; Martins A; Shuman S; and Mondragon A.;...
    EMBO J./20/p.2575-2586, 2001-01
  • The Length, Primary Structure and Phosphorylation State of the RNA Polymerase II CTD Dictate Interactions with the mRNA Capping Enzymes.
    Pei Y; Hausmann S; Ho CK; Schwer B; and Shuman S.; +HO KIONG
    J. Biol. Chem./276/p.28075-28082, 2001-01
Books
Conference, etc.
  • Structure and mechanism of archaeal ATP-dependent RNA ligase
    Ho Kiong; Yoshinari Shigeo; Murakami Katsuhiko S.
    Cutting Edge Developments in RNA Biology for the Control of Gene Expression/2017-11-13--2017-11-17
  • Messenger RNA recapping enzyme is regulated by hypermethylation at the 5’-end of the RNA
    Ho Kiong; Ignatochkina Anna V.; Iguchi Jesavel; Kore Anil...
    Cutting Edge Developments in RNA Biology for the Control of Gene Expression/2017-11-13--2017-11-17
  • Molecular Mechanism of mRNA Recapping in Trypanosome
    HO KIONG
    2017年度生命科学系学会合同年次大会/2017-12-06--2017-12-09
  • Identification and characterization of a novel 5'-monophosphate RNA kinase in Trypanosoma brucei
    Ho Kiong
    21th Annual RNA Society Meeting/2016-06-28--2016-07-02
  • Recapping the Message: The mRNA Decapping and Recapping Pathway in Trypanosomes
    Ho Kiong
    21th Annual RNA Society International Meeting/2016-06-28--2016-07-02
  • Inhibitor Screening Against Trypanosoma cruzi RNA Triphosphatase
    Ho Kiong; Takagi Yuko; Kuwabara Naoyuki; Tani Osamu; Saka...
    Kinetoplastid Molecular Cell Biology 2017/2017-04-22--2017-04-26
  • Archaea RNA Ligase is Required for Circularizing Small Non-Coding RNA.
    Ho Kiong; Liu Yancheng; Takagi Yuko; Hirata Akira; Hori H...
    RNA Meeting 2017 in Toyama/2017-07-19--2017-07-21
  • Trypanaosome mRNA recapping activity is modulated by hypermethylation derived from cap 4 structure
    Ho Kiong; Ignatochkina Anna V.; Iguchi Jesavel; Kore Anil...
    RNA Meeting 2017 in Toyama/2017-07-19--2017-07-21
Teaching
2018-10 -- 2019-02International Medical Sciences Exchange Program IUniversity of Tsukuba.
2018-10 -- 2019-02International Medical Sciences Exchange Program IIUniversity of Tsukuba.
2018-10 -- 2019-02International Medical Sciences Exchange Program IIIUniversity of Tsukuba.
2018-04 -- 2018-08International Medical Sciences Exchange Program IUniversity of Tsukuba.
2018-04 -- 2018-08International Medical Sciences Exchange Program IIUniversity of Tsukuba.
2018-04 -- 2018-08International Medical Sciences Exchange Program IIIUniversity of Tsukuba.
2018-10 -- 2019-02Dissertation in Medical SciencesUniversity of Tsukuba.
2018-10 -- 2019-02Internship IUniversity of Tsukuba.
2018-10 -- 2019-02Internship IIUniversity of Tsukuba.
2018-10 -- 2019-02Seminar on Basic Medical SciencesUniversity of Tsukuba.
Other educational activities
2017-02 -- 2017-03Undergraduate Medical Science CourseUniversity of Tsukuba
2017-02 -- 2017-02Biomedical Research Workshop in South East AsiaUniversity of Indonesia Medical Campus
2017-08 -- 2017-09Infection Diagnosis WorkshopBiotechnology Center of HCMC
2018-08 -- 2018-08International Medical Science Training CourseUniversity of Medicine and Pharmacy HCMC
2017-07 -- 2017-08Summer Research Program in Tsukuba 2017University of Tsukuba
2016-01 -- 2016-01Advanced Biotechnology and MedicineHCMC University of Science Vietnam
2015-01 -- 2015-01Advanced Biotechnology and MedicineHCMC University of Science Vietnam
2014-01 -- 2014-01Advanced Molecular BiologyHCMC University of Science Vietnam
2014-03 -- 2014-03Molecular Biology Course in VietnamUniversity of Tsukuba & Institute of Tropical Biology
2015-01 -- 2015-01Molecular Biology Course in VietnamUniversity of Tsukuba & Institute of Tropical Biology
University Management
2018-04 -- (current)医学医療系 国際連携委員会副役員長
2014-04 -- (current)医学生命システム 国際連携委員会委員
2018-04 -- (current)医療科学類 G30 国際連携委員会委員長
2016-04 -- (current)医療科学類 国際連携委員会役員
2018-04 -- (current)医療科学類 情報/広告委員会委員
2017-04 -- (current)医療科学類 カリキュラム委員会委員
2016-04 -- (current)HBP Academic Degree Committeemember
2014-04 -- (current)HBP Publicity CommitteeMember
2013-04 -- (current)HBP International AffairsMember

(Last updated: 2018-08-15)