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Okoshi Yasushi

face
Affiliation
Faculty of Medicine
Official title
Associate Professor
Email
 
Research fields
Hematology
Research keywords
悪性リンパ腫
Research projects
原発不明がんの治療成績向上を目的とした、がん組織由来マイクロRNAの網羅的解析2015 -- 2017大越 靖Japan Society for the Promotion of Science/Grant-in-Aid for Scientific Research(C)4,810,000Yen
Career history
2011-10 -- (current)Faculty of Medicine, University of Tsukuba
1995-06 -- 2001-03筑波大学附属病院 内科 レジデント
2005-04 -- 2011-09Graduate School of Comprehensive Human Sciences, University of Tsukuba 講師
Academic background
1989-04 -- 1995-04University of TsukubaGraduated
2001-04 -- 2005-03University of Tsukuba 人間総合科学研究科 先端応用医学Completed
Degree
2005-03博士(医学)University of Tsukuba
Licenses and qualifications
1995-04-28医師免許
2000-10-01日本内科学会認定内科医
2005-10-01日本血液学会認定血液専門医
2006-03-01日本血液学会認定血液指導医
Academic societies
2011 -- (current)THE JAPAN SOCIETY OF TRANSFUSION MEDIEINE AND CELL THERPY
1995 -- (current)THE JANPANESE SOCIETY OF INTERNAL MEDICINE
1997 -- (current)THE JAPANESE SOCIETY OF HEMATOLOGY
2008 -- (current)The Japanese Cancer Association
2008 -- (current)Japan Society for Hematopoietic Cell Transplantation
2011 -- (current)American Society of Hematology
Articles
  • A single institutional retrospective evaluation for younger patients with primary central nervous lymphomas on a modified R-MPV regimen followed by radiotherapy and high dose cytarabine
    Hattori Keiichiro; Sakata-Yanagimoto Mamiko; Okoshi Yasus...
    Journal of Clinical and Experimental Hematopathology/Advance Publication, 2017-08
  • MYD88 (L265P) mutation is associated with an unfavourable outcome of primary central nervous system lymphoma
    Hattori Keiichiro; Sakata-Yanagimoto Mamiko; Okoshi Yasus...
    British journal of haematology/177(3)/pp.492-494, 2016-05
  • Measurement of proteasome activity in peripheral blood mononuclear cells as an indicator of susceptibility to bortezomib-induced severe neurological adverse events in patients with multiple myeloma
    大越 靖
    Acta Haematologica/134/pp.25-31, 2015
  • Efficacy and safety of bortezomib-containing induction chemotherapy for autologous stem cell transplantation-eligible Japanese multiple myeloma patients -A phase 2 multicenter trial-
    Okoshi Yasushi
    International J Myeloma/pp.15-22, 2015-05
  • Adverse Effects of Morphine and Fentanyl for Stomatitis in Patients Receiving Allogeneic Hematopoietic Cell Transplantation—A Single Center Retrospective Analysis
    Okoshi Yasushi
    Open Journal of Blood Diseases, 2012-04
  • Soluble Recombinant Thrombomodulin Is a Potentially Promising Agent without Causing Severe Hemorrhagic Events for Hematological Malignancy-Induced Disseminated Intravascular Coagulation
    Kurita Naoki; Nishikii Hidekazu; Yokoyama Yasuhisa; Sakat...
    BLOOD/120(21), 2012-11
  • First-Line Treatment and Outcome of Elderly Patients with Primary Central Nervous System Lymphoma (PCNSL) - A Systematic Review and Individual Patient Data Meta-Analysis
    Kasenda Benjamin; Ferreri Andres J. M.; Maturano Emerenzi...
    BLOOD/120(21), 2012-11
  • 造血幹細胞移植後の水痘ウイルス感染症
    秋山秀樹; 井上 崇; 大越 靖; 森慎一郎; 大橋一輝; 前田義治;...
    臨床血液/41巻/p.20-24, 2000-01
  • Detection of minimal residual disease in a patient having acute myelogenous leukemia with t(16; 21)(p11; q22) treated by allogenic bone marrow transplantation.
    Y.Okoshi; S. Shimizu; H. Kojima; N. Obara; H. Y. Mukai; ...
    Acta Haematologica/105(1)/pp.45-48, 2001-01
  • Effect of additional chromosomal abnormalities in acute promyelocytic leukemia treated with all-trans retinoic acid: a report of 17 patients.
    Y. Okoshi; H. Akiyama; N. Kono; T. Matsumura; D. Mizuchi;...
    International Journal of Hematology/73/p.496-501, 2001-01
  • Nodal CD8 positive cytotoxic T-cell lymphoma: distinct clinicopathological entity.
    H. Y. Mukai; Y. Hasegawa; H. Kojima; Y. Okoshi; N. Takei;...
    Modern Pathology/15(11)/pp.1131-1139, 2002-01
  • A patient with acquired pure red cell aplasia showing a positive antiglobulin test and the presence of inhibitor against erythroid precursors.
    Y. Okoshi; S. Imagawa; M. Higuchi; C. Yoshida; S. Shimizu...
    Internal Medicine/41/p.589-592, 2002-01
  • 長期間持続している特発性第V因子インヒビター
    大越 靖; 秋山秀樹; 井上 崇; 小山高敏; 河野奈津; 松村有子;...
    臨床血液/44/p.14-18, 2003-01
  • Successful treatment of a patient with subcutaneous panniculitis-like T-cell lymphoma with high-dose chemotherapy and total body irradiation.
    H. Y. Mukai; Y. Okoshi; S. Shimizu; Y. Katsura; N. Takei;...
    European Journal of Haematology/70/p.413-416, 2003-01
  • Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation.
    K. Yotsumoto; Y. Okoshi; K. Shibuya; S. Yamazaki; S. Taha...
    Journal of Experimental Medicine/198/p.223-233, 2003-01
  • HLA-C Matching Status Does Not Affect Rituximab-Mediated Antibody-Dependent Cellular Cytotoxicity by Allogeneic Natural Killer Cells
    Machino T; Okoshi Y; Miyake Y; Akatsuka Y; Chiba S
    Immunological Investigation, 2012-01
  • Hepatosplenic alphabeta T-cell lymphoma successfully treated with allogeneic bone marrow transplantation.
    6.Machino T; Okoshi Y; Kaneko S; Obara N; Mukai H; Suzuka...
    Bone Marrow Transplant./39(8)/p.513-514, 2007-01
  • Pseudoaneurysm of the subclavian artery due to Xanthomonas pneumonia a in a patient with acute myeloid leukemia : its rupture treated by transcatheter embolization.
    Okoshi Y; Ninomiya H; Mukai HY; Mochizuki N; Hori M; Naga...
    Internal Medicine/38(8)/p.671-674, 1999-08
  • Relapse of acute meyloid leukemia with t(16;21)(p11;q22)mimicking autoimmune pancreatitis after second allogeneic bone marrow transplantation.
    Kamada Y; Suzukawa K; Taoka K; Okoshi Y; Hasegawa Y; Chib...
    ISRN Hematol/2011/p.285487, 2011-01
  • T-cell Prolymphocytic Leukemia with CD4^+8^+25^+ Phenotype in a Patient Presenting with Venous Thrombosis in the Lower Leg
    小原 直; 大越 靖; 向井 陽美; 米野 琢哉; 長谷川 雄一; 小島...
    臨床血液/40(11)/pp.1187-1192, 1999-11
  • Treatment Outcome of Adult Burkitt Lymphoma in Japanese Patients with Modified LMB Protocol : A Single Center Retrospective Analysis
    NISHIKII Hidekazu; NAKAMURA Naoya; KONDO Yuzuru; OKOSHI Y...
    Journal of Clinical and Experimental Hematopathology/51(2)/pp.109-114, 2011-11
  • Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor
    Nakahashi-Oda Chigusa; Tahara-Hanaoka Satoko; Shoji Masam...
    JOURNAL OF EXPERIMENTAL MEDICINE/209(8)/pp.1493-1503, 2012-07
  • Nine years interval between first and second bone marrow transplantations and subsequent long-term survival-a case of acute myeloid leukemia with MLL-AF6 fusion gene
    Yokoyama Yasuhisa; Suzukawa Kazumi; Okoshi Yasushi; Nanmo...
    ANNALS OF HEMATOLOGY/91(9)/pp.1491-1493, 2012-09
  • Isolated Cardiac Involvement of B-Cell Acute Lymphoblastic Leukemia Mimicking Acute Myocardial Infarction With Persistent Broad ST-Segment Elevationc
    Kakefuda Yuki; Sato Akira; Hoshi Tomoya; Ishizu Tomoko; T...
    CIRCULATION/125(22)/pp.E979-E982, 2012-06
  • A lower starting dose of eltrombopag is efficacious in Japanese patients with previously treated chronic immune thrombocytopenia
    Tomiyama Y.; Miyakawa Y.; Okamoto S.; Katsutani S.; Kimur...
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS/10(5)/pp.799-806, 2012-05
Books
  • 先天性リンパ球減少症
    大越 靖
    別冊日本臨床 新領域別症候群シリーズ No.22 血液症候群(第2版)/pp.204-207, 2013-03
  • Requirement of the tyrosines at residues 258 and 270 of MAIR-I in inhibitory effect on degranulation from basophilic leukemia RBL-2H3.
    大越 靖
    2005-03
  • 分子レベルからみたT/NK細胞分化
    大越 靖; 渋谷 彰
    2005-08
  • ペアレセプターMAIR-I・MAIR-IIによる骨髄球系細胞の活性化制御機構
    大越 靖; 中橋 ちぐさ; 渋谷 彰
    2004-01
  • Treatment of PNH hemolytic crisis with heparin or low-molecular weight heparin by its dual (anti-complement and anti-coagulant) activity.
    Yoshida C; Okoshi Y; Hasegawa Y; Nagasawa T; Ninomiya H
    2003-01
  • KIR (Killer cell Immunoglobulin-like receptors)
    大越 靖; 渋谷 彰
    2003-01
  • MAIRファミリー分子と正と負の自然免疫制御
    大越 靖; 四本 克己; 渋谷 彰
    2003-01
  • 骨髄球系細胞の活性化制御を担う新しいpaired receptor; MAIR
    四本 克己; 大越 靖; 渋谷 彰
    2002-01
Conference, etc.
  • 多発性骨髄腫患者の血清中サイトカイン・ケモカインの網羅的測定に基づく病態・予後解析
    張 愉紀子; 稲田 勝重; 越野 繭子; 大越 靖; 堀 光雄; 小島 寛
    第41回日本骨髄腫学会学術集会/2016-5-29
  • 茨城県合同輸血療法委員会の廃棄血削減へ向けた取り組み
    谷川道浩; 大江和紀; 山口恭子; 羽石靖浩; 石野はるみ; 佐藤...
    第17回日本医療マネジメント学会茨城県支部学術集会/2016-9-3
  • Efficacy and safety of CBD induction for ASCT-eligible NDMM -A phase 2 multicenter trial-
    Kudo K; Ohashi K; Nakamura Y; Shinagawa A; Suyama T; Yosh...
    第78回日本血液学会学術集会/2016-10-13--2016-10-15
  • The prognostic impact of c-kit D816 mutations in core binding factor acute myeloid leukemia
    Yui S; Kurosawa S; Yamaguchi H; Kanamori H; Ueki T; Uoshi...
    第78回日本血液学会学術集会/2016-10-14
  • The impact of FLT3-ITD, NPM1 and CEBPA on prognosis of intermediate-risk AML after relapse
    Kurosawa S; Yamaguchi H; Yamaguchi T; Fukunaga K; Yui S; ...
    第78回日本血液学会学術集会/2016-10-13
  • Modulated mRNA expression profiles of a MM cell after a long-term exposure to lenalidomide
    Hori M; Okoshi Yasushi; Fujio T; Kojima H; Aha H; Ikebe E
    第78回日本血液学会学術集会/2016-10-13
  • The glycoproteins expression pattern analysis on lenaridomide sensitive /non-sensitive MM cell-lines
    大越 靖
    第75回日本血液学会学術集会/2013-10-11--2013-10-13
  • Retrospective analysis of azacitidine for high-risk myelodysplastic syndromes
    大越 靖
    第75回日本血液学会学術集会/2013-10-11--2013-10-13
  • Two cases of intravascular lymphoma: Usefulness of a skin biopsy
    大越 靖
    第75回日本血液学会学術集会/2013-10-11--2013-10-13
  • Analysis of the availability of circulating microRNAs for detection of non-Hodgkin lymphoma
    大越 靖
    第75回日本血液学会学術集会/2013-10-11--2013-10-13
  • Comprehensive analyses of circulating cytokines / chemokines in patients with multiple myeloma
    大越 靖
    第75回日本血液学会学術集会/2013-10-11--2013-10-13
  • Treatment model of CNS Lymphoma using complement-dependent cytotoxicity induced by rituximab and autoserum
    Miyake Y; Okoshi Yasushi; MachinoT; Chiba S
    51st American Society of Hematology annual meeting/2009-12-7
  • 高齢者の中枢神経原発悪性リンパ腫に対する、メソトレキセートを減量した非照射レジメンの治療成績
    田岡 謙一; 大越 靖; 鈴川 和己; 坂本 規彰; 高野 晋吾; ...
    第107回日本内科学会総会・講演会/2010-4-10
  • Outcome of methotrexate-based chemotherapy without whole-brain-irradiation in elderly PCNCL
    Taoka K; Okoshi Y; Suzukawa K; Takano S; Matsumura A; Shi...
    第72回日本血液学会総会/2010-09-26
  • Analysis of the glycoproteins expression pattern in refractory multiple myeloma
    Mitsuo Hori; 大越 靖; Sousuke Meshitsuka; Hiromi Yuasa; H...
    第74回日本血液学会学術集会/2012-10-19
  • Prediction of bortezomib-induced severe neurologic events by monitoring protease activity in PBMC
    Yukiko Cho; Mitsuo Hori; 大越 靖; Hiromi Yuasa; Takuya Ko...
    第74回日本血液学会学術集会/2012-10-19
  • The response to azacytidine in high-risk myelodysplastic syndrome
    Atsushi Shinagawa; Daisuke Kudo; Takuya Komeno; Chikashi ...
    第74回日本血液学会学術集会/2012-10-20
  • A phase I study of weekly bortezomib for Japanese patients with recurrent or refractory myeloma
    Atsushi Shinagawa; 大越 靖
    第74回日本血液学会学術集会/2012-10-20
  • A Non-radiation, Intermediate-dose MTX Regimen for Elderly CNS DLBCL patients - an updated analysis
    Yasushi Okoshi; Kenichi Taoka; Shingo Takano; Akira Matsu...
    第74回日本血液学会学術集会/2012-10-20
  • Drug interaction between aprepitant and prednisolone in patients treated with (R)-CHOP
    Koichiro Maie; Yasushi Okoshi; Naoki Kurita; Masato Honma...
    第74回日本血液学会学術集会/2012-10-21
  • First-Line Treatment and Outcome of Elderly Patients with Primary Central Nervous System Lymphoma (PCNSL) – A Systematic Review and Individual Patient Data Meta-Analysis
    Benjamin Kasenda; Andrés J.M. Ferreri; Emerenziana Matura...
    The American Society of Hematology 54th Annual Meeting and Exposition/2012-12-10
  • 造血器腫瘍早期診断のための血清マイクロRNAに関する研究
    稲田勝重; 張愉紀子; 大越 靖; 堀光雄; 三橋彰一; 小島寛
    第22回 茨城がん学会/2013-02-03
  • 悪性リンパ腫のお話し
    大越 靖
    血液疾患市民公開セミナー 茨城県内の血液医療について/2011-11-05
  • A Non-Radiation-Containing, Intermediate-Dose Methotrexate (MTX) Regimen Resulted in Favorable Survival without Progression of Dementia in Elderly Patients with Primary Central Nervous System Lymphoma (PCNSL)
    Taoka Kenich; Okoshi Yasushi; Hasegawa Yuichi; Chiba Shigeru
    51st Annual Meeting of the American-Society-of-Hematology/2009-12-06
  • Six Month Treatment of Low Dose Eltrombopag Is Efficacious in Japanese Patients with Refractory Chronic Immune Thrombocytopenic Purpura (ITP)
    Tomiyama Yoshiaki; Miyakawa Yoshitaka; Okamoto Shinichiro...
    51st Annual Meeting of the American-Society-of-Hematology/2009-12-5
Teaching
2017-10 -- 2018-02Hematological oncologyUniversity of Tsukuba.
2017-04 -- 2017-08Hematological oncologyUniversity of Tsukuba.
2017-10 -- 2018-02Basic OncologyUniversity of Tsukuba.
2017-04 -- 2017-08Basic OncologyUniversity of Tsukuba.
2017-10 -- 2018-02Clinical Oncology: Hematogenous cancerUniversity of Tsukuba.
2017-04 -- 2017-08Clinical Oncology: Hematogenous cancerUniversity of Tsukuba.
2017-04 -- 2017-08Advanced Exercise on Public HealthUniversity of Tsukuba.
2017-10 -- 2018-02Advanced Exercise on Public HealthUniversity of Tsukuba.
2017-04 -- 2017-08Internship IIUniversity of Tsukuba.
2017-10 -- 2018-02Internship IIUniversity of Tsukuba.
Talks
  • 静注ブスルファンによる前処置後の移植後胃前庭部毛細血管拡張症
    福田匡芳; 栗田尚樹; 坂本竜弘; 錦井秀和; 横山泰久; 坂田麻...
    第31回 茨城造血器疾患研究会/2011-05-28
  • 発症から8年経過し再発後の治療が奏功しているT細胞性中枢神経原発リンパ腫の症例
    真家 紘一郎; 鈴川 和己; 坂本 竜弘; 福田 匡芳; 日下部 学; ...
    第166回 日本血液学会例会/2011-07-02
  • Effect and safety of rabbit anti-thymocyte globulin (ATG) for aplastic anemia
    Tatsuhiro Sakamoto; Naoshi Obara; Rie Matsubara; Kuniyosh...
    第73回日本血液学会学術集会/2011-10-14
  • Post-transplant gastric antral vascular ectasia with intra-venous busulfan-containing regimen
    Kuniyoshi Fukuda; Naoki Kurita; Tatsuhiro Sakamoto; Hidek...
    第73回日本血液学会学術集会/2011-10-15
  • Long-term safety and efficacy of eltrombopag in patients with previously treated chronic ITP
    Shinya Katsutani; Yoshiaki Tomiyama; Akiro Kimura; Yoshit...
    第73回日本血液学会学術集会/2011-10-15
  • Analysis of whole genome copy number abnormalities in multiple myeloma patients
    Yuhei Kamada; Mamiko Sakata-Yanagimoto; Masashi Sanada; A...
    第73回日本血液学会学術集会/2011-10-16
  • Prednisolone vs. high-dose dexamethazone for untreated primary immune thrombocytopenic purpura
    Kana Sakamoto; Hideki Nakasone; Shigeharu Tsurumi; Ko Sas...
    第73回日本血液学会学術集会/2011-10-16
  • Outcomes of splenectomy for adult patients with ITP – a single center retrospective analysis
    Yasushi Okoshi; Naoki Kurita; Hidekazu Nishikii; Yasuhisa...
    第73回日本血液学会学術集会/2011-10-16
  • 成人ITPに対する脾摘成績―単施設、後方視的解析
    大越 靖; 栗田 尚樹; 錦井 秀和; 横山 泰久; 柳元 麻実子; 小...
    第109回日本内科学会講演会/2012-04-13
  • 同種造血幹細胞移植後再発白血病に対するHSV-TK遺伝子導入ドナーリンパ球輸注療法―成人3症例の臨床経過
    大越靖; 金子新; 小野寺雅史; 大津真; 南木融; 根本範子; 越...
    第68回日本血液学会・第48回日本臨床血液学会合同総会/2006-10-08

(Last updated: 2017-05-14)